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Precision GLP-1 · Las Vegas + Telehealth

Lose the weight.Define the result.

Physician-directed GLP-1 and peptide protocols — calibrated to your body, priced flat, delivered discreet.

  • Physician-directed
  • Flat-rate pricing
  • Discreet delivery
A TIGHTENRx patient on a precision GLP-1 protocol
Defined results

from$199/mo

$0 if you are not approved

Physician-directed
Titrated to you
Flat-rate pricing
Discreet cold-chain delivery
Secure messaging
Telehealth nationwide
Defined results
Physician-directed
Titrated to you
Flat-rate pricing
Discreet cold-chain delivery
Secure messaging
Telehealth nationwide
Defined results
Defined results at the end of a precision protocol

Why precision wins

Every milligram measured.Every week, supported.

Anyone can mail you a medication. We dial the dose to your body and hold the line on your result — clinically supervised, start to goal.

50States · telehealth access
$0If you are not approved
100%Physician-reviewed plans
3 minTo start your assessment

The method

A protocol, not a refill.

Built around your biology
Physician-directed
01

Calibrate

Built around your biology

A licensed provider reviews your full profile and sets a starting dose tuned to you — then adjusts as your numbers move.

Dialed in, week after week
Secure messaging
02

Support

Dialed in, week after week

Secure messaging keeps your clinical team a tap away between check-ins. Recovery, side-effects, momentum — all monitored.

One flat price, all-in
Flat-rate
03

Sustain

One flat price, all-in

Visit, medication, and discreet cold-chain delivery in a single transparent rate. No insurance maze, no surprise fees.

Data & Evidence

Visualize your clinical trajectory.
Backed by medical science.

Explore typical treatment milestones across weeks of supervised therapy. Interact with the tracker below to see progress indicators.

Week 12 Clinical Milestone
-9.8%Average reduction: -14.1 lbs

Physiological Effect

Clinically notable progress

In clinical trials, provider-supervised GLP-1 patients maintained continuous clinical weight loss over 24 weeks with a balanced metabolic protocol.

Move your finger or mouse across the chart to scrub through milestones.
Week 0Week 12 (Midpoint)Week 24 (Target)
ACTIVE CHART
StartMonth 1Month 2Month 3Month 4Month 5Month 6

* References: Average weight loss percentage and metabolic metabolic markers sourced from multi-center, placebo-controlled national clinical trials of Compounded Semaglutide and Tirzepatide formulations at 24 weeks of active treatment. Individual health profiles and outcomes vary. Eligibility is determined only after complete clinical provider evaluation.

How We Care

A secure, clinician-led
care experience.

From your first secure online intake form to continuous provider-guided support, we verify clinical appropriateness at every single milestone.

Step 01 of 05

100% online intake

Complete a secure, HIPAA-compliant assessment from home detailing your health history, weight goals, and baseline metrics at your own pace.

  • No appointments or clinic visits needed
  • Saves patient intake securely in encrypted form
  • Takes about 5–10 minutes to complete
TIGHTENRx compounded GLP-1 vial

In their words

Results worth standing behind.

After fifteen years of trying everything, the food noise just stopped. The first week was strange. The first month was the proof. I am still surprised.
Sarah M.TIGHTENRx member · 9 months on Semaglutide
What I did not expect was how normal it would feel. I am not white-knuckling anything. I eat when hungry and stop when full. That is the whole story.
Michael T.TIGHTENRx member · 6 months on Semaglutide
My provider adjusted my dose three times to find what worked for me. That kind of attention is what I never got from regular doctors. The supervision is what makes this safe.
Jessica R.TIGHTENRx member · 7 months on Semaglutide
GLP-1 weight loss
Peptide therapy
No insurance maze
$0 if you are not approved
Precision, by protocol
Las Vegas + nationwide
GLP-1 weight loss
Peptide therapy
No insurance maze
$0 if you are not approved
Precision, by protocol
Las Vegas + nationwide

Eligibility tool

See if you may be a candidate — in seconds

Estimate your BMI to understand where you land. It's a starting point — a licensed provider confirms eligibility during your assessment.

BMI calculator inputs
5'7"
4'6"7'0"
190 lbs
90 lbs400 lbs

Your estimated BMI

29.8Elevated range
HealthyElevatedHigher

You're near common GLP-1 criteria. With a weight-related condition, a provider may still consider treatment — the assessment confirms your fit.

Start secure assessment

Plans from $199/mo · confirmed after provider review

Educational estimate only. BMI is one factor; a licensed provider determines eligibility and the right treatment for you.

Common questions

Answers before you start.

Clear, honest information about treatment, eligibility, and what to expect. A licensed provider confirms everything during your assessment.

Start with a short online assessment about your health goals and basic medical history. A licensed clinician reviews it and, if clinically appropriate, creates a personalized plan and coordinates care. Follow-ups are scheduled as needed so your plan can be adjusted over time. Prescription treatments are offered only when safe and appropriate, and work best alongside sustainable habits and ongoing medical guidance.

Your result starts with one honest assessment.

A few minutes, no obligation. You only move forward when a licensed provider says it is right for you — and if you are not approved, you are not charged.

From $199/mo

$0 if not approved

Check Eligibility